Howard held a personal chair at the Royal Free Hospital and then the departmental chair of medicine at St Mary’s Hospital Medical School. Following the formation of Imperial College Medical School, he became Head of Hepatology and Gastroenterology. He is currently an Emeritus Professor at Imperial.
Howard has been the President of the British and European Liver Societies and received their Life-Time Achievement Awards. He was awarded the Hans Popper International Award for distinction in Liver Disease 1989, the Ivanovsky Medal of the Russian Academy of Medical Sciences 1997 and The Imperial College Medal in 2011.
He has also been Chairman of the Department of Health Advisory Group on Hepatitis, the Chairman of the Hepatitis C Strategy Group preparing the Hepatitis C Action Plan a member of the Joint Committee on Vaccination and Immunisation Subgroup on Hepatitis B vaccination, the Department of Health Committee on New and Emerging Pathogens and a member of several WHO Advisory Groups. He was Chair of the NICE Hepatitis B Guidelines Group.
Howard has described the molecular variants of Hepatitis B Virus (HBV), made monoclonal antibody based immunoassays to HBV licensed to several companies and contributed to the development of interferon based treatment for Hepatitis B and C in multi-centre international trials.
He has published many publications and several books and book chapters.
Howard was a founding scientist of Riotech Pharmaceuticals in 2002 and is currently Chairman and Chief Scientist.